Daniel Probst
@skepteis
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Computer scientist, Bioinformatician, PhD in Chemistry and Molecular Sciences. Interested in all the sciences. Materialist. Fan of cats, Punk Rock, and Hockey.
Switzerland
Joined January 2017
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Pinned Tweet
A map of all approved, illicit, and experimental drugs.
A fully interactive Faerun visualization of
@DrugBankDB
embedded using TMAP from 2²³ dimensional MHFP space. This combines 4 projects I have been working on so far during my PhD.
Check it out here:
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Daniel Probst Retweeted
Geschäftsmodell
#Impfschaden
Ich bin sprachlos, wie munter
#Heilpraktiker
, aber auch #Ärzte Impfschäden diagnostizieren und sich dann fürstlich für deren alternativ-ganzheitliche Behandlung bezahlen lassen.
Patienten sind dankbar, dass ihre Beschwerden eine Ursache haben.
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Die Sinophobie die
@srfnews
in den moderierten Kommentaren zulässt ist übel.
Von "die Chinesischen Studis werden eh alle von der Regierung geschickt" bis "die können alle nix und die sind nur da weil Cnina die Löhne bezahlt" alles dabei.
Ekelhaft.
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Daniel Probst Retweeted
Dank einer Zusammenarbeit der
#unibern
mit dem Archäologischen Dienst des
@KantonBern
konnte Prof. Dr. Christa Ebnöther zur spätantiken Grabungsstätte Kallnach im Berner Seeland neue Erkenntnisse gewinnen. Die Ergebnisse liegen nun in Buchform vor:
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Ah, the new backbone editing technique 😁
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Daniel Probst Retweeted
Scientifically speaking, poxviruses, such as monkeypox, are pretty cool.
Unlike other DNA viruses they do not need to enter the host cell's nucleus to replicate. They replicate inside so-called viroplasms in the cytoplasm of the cell.
(Image: E. Zonov et al, description below)
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Hey
#chemtwitter
, I put together a colab notebook with my model for predicting Buchwald-Hartwig reaction yields. You can give it a try using the link below if you're interested. Usual ML caveats apply.
The model is trained on data set by Ahneman et al.
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After this is done those virosomes, which are also called virus factories, start churning out viruses.
This seems to help the virus escape host defences. Other viruses that do this are herpes and rota viruses
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So the virus gets into this cell and induces changes that form these virosome regions where it deposits its genetic material and enzymes needed for replication. It then starts to recruit mitochondria (** in the image above) and required proteins from the host.
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In the image, * marks the viroplasms.
Photos A and B show the immature round pox virus particles, images C and D the mature ones. Images E–F shows the virus particle being enveloped using the Golgi apparatus.
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Scientifically speaking, poxviruses, such as monkeypox, are pretty cool.
Unlike other DNA viruses they do not need to enter the host cell's nucleus to replicate. They replicate inside so-called viroplasms in the cytoplasm of the cell.
(Image: E. Zonov et al, description below)
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