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Allysa Warling Profile
Allysa Warling

@AllysaWarling

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MD student @harvardmed | formerly @NIMHgov & @coloradocollege xc/tf

Boston, MA
Joined June 2020
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@AllysaWarling
Allysa Warling
a year ago
Really interesting deep dive at the intersection of sex-based differences, alcohol use, and the brain!! 🤩so proud of Ethan & Catherine's work here.
@ethanwhitman777
ethan whitman
a year ago
new article from @bogglerapture lab co-led with @catherinemankiw now out in @eic_nic ! we leveraged a unique longitudinal neuroimaging dataset to identify sex-biased relationships between brain anatomy in childhood and adult drinking behavior
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Allysa Warling Retweeted
@HistedLab
Histed Neuroscience Lab
a year ago
Crossing the streams here and sharing a side proj, from my non-science Twitter: I think that boosting journalism could do a lot to fix the problems facing the US. I wrote something about why we need public subsidies for news, and how best to provide that — via news vouchers.
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@AllysaWarling
Allysa Warling
a year ago
... | And my home team in the Section on Developmental Neurogenomics -- @NadigAjay @CassidyLMcD @bogglerapture @jakob_seidlitz & Siyuan Liu -- for their unwavering commitment, mentorship, leadership, and support (15/15).
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@AllysaWarling
Allysa Warling
a year ago
I want to thank @edbullmore @CamNeuro | @sattertt , Ruben & Raquel Gur, David Roalf, & Tyler Moore @PennMedicine | David Glahn & Amanda Rodrigue @harvardmed (14/15) ...
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@AllysaWarling
Allysa Warling
a year ago
I am so proud to have been a part of this project, which was the result of an incredible collaboration across several institutions (13/15).
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@AllysaWarling
Allysa Warling
a year ago
...we believe our findings provide important context for studies on cortical and subcortical gray matter, and can also serve as critical benchmarks for future work on white matter, in both health and disease (12/15).
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@AllysaWarling
Allysa Warling
a year ago
Why is this work important? As the first spatially-comprehensive maps of regional white matter changes across normative human brain size variation (11/15)...
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@AllysaWarling
Allysa Warling
a year ago
...which suggests that the relative white matter volume expansion/contractions we observed were not underwritten by microstructural/myelin-related processes, although more work remains to be done on this point (10/15).
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@AllysaWarling
Allysa Warling
a year ago
Notably, we also demonstrated that brain size-related volumetric white matter changes were spatially distinct from size-related changes in two common measures of white matter microstructure (fractional anisotropy / FA and magnetization transfer / MT)(9/15)...
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@AllysaWarling
Allysa Warling
a year ago
As brains become larger, both higher-order associative cortices & the white matter tracts that connect them become relatively expanded, while regions & tracts dedicated to sensory/ motor functions become relatively diminished (8/15).
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@AllysaWarling
Allysa Warling
a year ago
Thus, there appears to be a coordinated coupling of gray and white matter changes with naturally-occurring human brain size variation (7/15):
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@AllysaWarling
Allysa Warling
a year ago
...AND these reproducible white matter changes followed the patterns previously established in gray matter (6/15).
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@AllysaWarling
Allysa Warling
a year ago
Importantly, these volumetric changes replicated across all three cohorts that we examined (5/15)....
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@AllysaWarling
Allysa Warling
a year ago
We found that some white matter regions (i.e., underlying frontal/parietal areas, and parts of the corpus callosum) showed relative volumetric expansion in larger brains, while others (i.e., subcortical tracts in the brainstem and cerebellum) showed relative contraction (4/15).
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